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Hspa9 is required for pronephros specification and formation in Xenopus laevis

Gassié L, Lombard A, Moraldi T, Bibonne A, Leclerc C, Moreau M, Marlier A and Gilbert T
Development of the pronephros in Xenopus laevis is largely dependent on retinoic acid signaling at the time (...)

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In vivo dynamics of skeletal muscle Dystrophin in zebrafish embryos revealed by improved FRAP analysis eLIFE (in press)

Fernanda Bajanca, Vinicio Gonzalez-Perez, Sean J. Gillespie, Cyriaque Beley, Luis Garcia, Eric Theveneau, Richard P. Sear, Simon M. Hughes.

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Kcnip1 a Ca2+-dependent transcriptional repressor regulates the size of the neural plate in Xenopus. Biochim Biophys Acta. 2014 Dec 9.

published by Néant I, Mellström B, Gonzales P, Naranjo JR, Moreau M, Leclerc C.
In amphibian embryos, our previous work has demonstrated that calcium transients occurring in the dorsal ectoderm at (...)

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Laurence Garric, Brice Ronsin, Myriam Roussigné, Sabrina Booton, Joshua T. Gamse, Pascale Dufourcq and Patrick Blader. "Pitx2c ensures habenular asymmetry by restricting parapineal cell number". Development, 141(7) : 1572-1579.

Left-right (L/R) asymmetries in the brain are thought to underlie lateralised cognitive functions. Understanding how neuroanatomical asymmetries are established has been achieved through the (...)

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Le 18 mars Marc Moreau a reçu la médaille d’honneur du CNRS

Cette médaille récompense lors du départ à la retraite la qualité des services rendus à l’organisme et à la science.
Cette médaille a été remise par Patrick Mounaud, Délégué Régional du CNRS, en présence (...)

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Low affinity binding site clusters confer hox specificity and regulatory robustness. Cell. 2015

Crocker J, Abe N, Rinaldi L, McGregor AP, Frankel N, Wang S, Alsawadi A, Valenti P, Plaza S, Payre F, Mann RS, Stern DL. Cell. 2015 ;160(1-2):191-203
In animals, Hox transcription factors define (...)

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Osman Breig, Stéphanie Bras, Natalia Martinez Soria, Dani Osman, Olaf Heidenreich, Marc Haenlin and Lucas Waltzer. "Pontin is a critical regulator for AML1-ETO-induced leukemia." Leukemia, in press

The oncogenic fusion protein AML1-ETO, also known as RUNX1-RUNX1T1 is generated by the t(8 ;21)(q22 ;q22) translocation, one of the most frequent chromosomal rearrangements in acute myeloid (...)

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